منابع مشابه
Iron Overload and Thalassemia Minor: Association With HLA-Linked Hemochromatosis
A pedigree was studied in which five individuals with fl-thalassemia minor were found to have nontransfusional hemochromatosis. Three were children under the age of 10 and two were young male adults. ages 28 and 33. A 5-yr-old child without evidence of thalassemia also had hemochromatosis. Since hemochromatosis is transmitted as an HIA-linked autosomal recessive disorder. HLA haplotypes serve a...
متن کاملNontransfusional iron overload in thalassemia. Association with hereditary hemochromatosis.
genes. Hemochromatosis is inherited as an autosomal recessive trait and The Cys282Tyr mutation was detected in only 1 of the 81 individis manifested by excessive absorption of dietary iron in homozygotes uals with thalassemia intermedia. The proband presented in 1975 at leading to complications of iron overload and premature death. In the age of 42 years with joint pains. Hepatomegaly was noted...
متن کاملDiabetic ketoacidosis and hypogonadotropic hypogonadism in association with transfusional hemochromatosis in a man with beta-thalassemia major.
We report a 23-year-old man with beta-thalassemia major and transfusional hemochromatosis, which manifested as diabetic ketoacidosis and hypogonadotropic hypogonadism. This unusual presentation of diabetic ketoacidosis in hemochromatosis has rarely been reported. Magnetic resonance imaging of the abdomen showed decreased signal intensity in the liver, spleen, and pancreas. In addition, the pitu...
متن کاملMalignancies in patients with beta-thalassemia major and beta-thalassemia intermedia: a multicenter study in Iran.
BACKGROUND Beta thalassemia is one of the most common genetic disorders in the world. The aim of this study was to determine the frequency, characteristics, and pattern of malignancies in patients with beta thalassemia major (BTM) and beta thalassemia intermedia (BTI) in Iran. METHODS We conducted a multicenter study via a retrospective chart review of patients with BTM and BTI between 2002 a...
متن کاملHematuria in patients with Beta-thalassemia major.
INTRODUCTION Our information about renal involvement in beta-thalassemia major is limited. Recently, few studies have reported proteinuria, hypercalcuria, phosphaturia, and oversecretion of tubular damage markers; however, hematuria has not yet been meticulously studied in these patients. We investigated hematuria in patients with beta-thalassemia major. MATERIALS AND METHODS Urinalysis was p...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Internal Medicine
سال: 1992
ISSN: 0918-2918,1349-7235
DOI: 10.2169/internalmedicine.31.1060